Table 3 Multivariate Cox regression analysis for overall survival.
Variable | Categories | MTV model | TLG model | Pseudotime model | |||
|---|---|---|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | ||
Age | < 66 vs. 66 ≤ | 2.371 (1.116–5.033) | 0.025 | 2.427 (1.141–5.163) | 0.021 | 2.413 (1.137–5.117) | 0.022 |
Adjuvant chemotherapy | No vs. yes | 0.177 (0.074–0.421) | < 0.001 | 0.174 (0.074–0.407) | < 0.001 | 0.166 (0.071–0.388) | < 0.001 |
Initial CEA | Low vs. high | 2.786 (1.367–5.677) | 0.005 | 2.727 (1.334–5.573) | 0.006 | 2.721 (1.338–5.533) | 0.006 |
Pathological T stage after CCRT | ypT0 vs. ypT1/is | 0.691 (0.071–6.704) | 0.750 | 0.731 (0.075–7.138) | 0.788 | 0.655 (0.067–6.388) | 0.875 |
ypT0 vs. ypT2 | 0.522 (0.144–1.894) | 0.323 | 0.583 (0.162–2.095) | 0.409 | 0.481 (0.133–1.740) | 0.301 | |
ypT0 vs. ypT3 | 0.581 (0.183–1.846) | 0.358 | 0.650 (0.204–2.069) | 0.466 | 0.541 (0.171–1.714) | 0.384 | |
ypT0 vs. ypT4 | 0.524 (0.096–2.870) | 0.456 | 0.478 (0.087–2.626) | 0.396 | 0.382 (0.070–2.093) | 0.558 | |
Pathological N stage after CCRT | ypN0 vs. ypN1 | 4.298 (1.873–9.863) | < 0.001 | 4.528 (1.947–10.532) | < 0.001 | 4.334 (1.873–10.027) | < 0.001 |
ypN0 vs. ypN2 | 10.204 (3.326–31.305) | < 0.001 | 11.239 (3.649–34.610) | < 0.001 | 10.250 (3.349–31.371) | < 0.001 | |
MTV | Low vs. High | 2.816 (0.968–8.194) | 0.057 | ||||
TLG | Low vs. High | 2.920 (0.781–8.718) | 0.080 | ||||
Pseudotime | Early vs. Late | 5.095 (1.187–21.874) | 0.028 | ||||
