Fig. 4

Genetic alterations, prognostic and diagnostic value of TMEM101 in HCC patients. (A) OncoPrint in cBioPortal showed the alteration frequency of TMEM101 in HCC. The different types of genetic alterations are highlighted in different colors. (B-C) Genetic alterations in TMEM101 were associated with shorter DFS (B) and OS (C) of HCC patients (cBioPortal database). (D) High expression of TMEM101 was correlated with worse OS in HCC patients. (E) Kaplan-Meier survival analysis of the prognostic value of TMEM101 in the ICGC validation set. (F) The ROC curve demonstrated the diagnostic value of TMEM101 in HCC patients. Abbreviations: OS: overall survival; DFS: disease free survival.