Table 2 Uni- and multivariable linear regression analyses of tomographic fat measurements with measured glomerular filtration rate standardized for BSA.

From: Higher abdominal fat area associates with lower donor kidney function before and after living kidney donation

All donors

mGFR screening (mL/min per 1.73 m2)

mGFR 3 months post-donation (mL/min per 1.73 m2)

Univariable

Β

Std. β

95% CI

p

 

Β

Std. β

95% CI

p

 

VATi

-0.14

-0.21

-0.19; -0.08

< 0.001

 

-0.10

-0.22

-0.14; -0.06

< 0.001

 

SATi

-0.11

-0.19

-0.16; -0.06

< 0.001

 

-0.11

-0.19

-0.16; -0.06

< 0.001

 

IMATi

-2.14

-0.31

-2.69; -1.59

< 0.001

 

-2.14

-0.31

-2.69; -1.59

< 0.001

 

TATi

-0.10

-0.26

-0.13; -0.07

< 0.001

 

-0.10

-0.26

-0.13; -0.07

< 0.001

 

Multivariable

Β

Std. β

95% CI

p

Adj. R2

Β

Std. β

95% CI

p

Adj. R2

VATi

Age at CT

Age at CT2

Female sex

mGFR at screening

-0.11

0.88

-0.01

-5.53

-0.18

0.63

-1.03

-0.18

-0.17; -0.06

0.13; 1.63

-0.02; -0.01

-8.04; -3.01

< 0.001

0.02

< 0.001

< 0.001

0.24

-0.07

0.05

-0.002

4.77

0.33

-0.15

0.05

-0.23

0.22

0.66

-0.10; -0.04

-0.38; 0.48

-0.01; 0.002

3.16; 6.38

0.29; 0.37

< 0.001

0.82

0.32

< 0.001

< 0.001

0.53

SATi

Age at CT

Age at CT2

Female sex

mGFR at screening

-0.10

0.79

-0.01

-1.12

-0.16

0.57

-1.01

-0.04

-0.15; -0.05

0.04; 1.54

-0.02; -0.01

-3.71; 1.46

< 0.001

0.04

< 0.001

0.39

0.24

-0.13

-0.20

0.002

12.7

0.72

-0.22

-0.14

0.12

0.41

0.98

-0.16; -0.11

-0.56; 0.17

-0.002; 0.01

11.3; 14.1

0.68; 0.75

< 0.001

0.29

0.38

< 0.001

< 0.001

0.83

IMATi

Age at CT

Age at CT2

Female sex

mGFR at screening

-1.18

0.73

-0.01

-3.82

-0.17

0.52

-0.90

-0.12

-1.73; -0.63

-0.02; 1.47

-0.02; -0.01

-6.14; -1.51

< 0.001

0.06

0.001

0.001

0.24

-1.56

-0.29

0.004

9.07

0.72

-0.23

-0.21

0.27

0.29

0.98

-1.82; -1.30

-0.65; 0.07

0.00; 0.01

7.83; 10.3

0.69; 0.75

< 0.001

0.11

0.04

< 0.001

< 0.001

0.83

TATi

Age at CT

Age at CT2

Female sex

mGFR at screening

-0.07

0.88

-0.01

-3.11

-0.18

0.63

-1.04

-0.10

-0.10; -0.04

0.13; 1.63

-0.02; -0.01

-5.41; -0.81

< 0.001

0.02

< 0.001

0.01

0.25

-0.09

-0.10

0.001

9.99

0.72

-0.23

-0.07

0.09

0.32

0.98

-0.10; -0.07

-0.45; 0.25

-0.002; 0.01

8.77; 11.2

0.69; 0.75

< 0.001

0.58

0.49

< 0.001

< 0.001

0.84

  1. mGFR, measured glomerular filtration rate (mL/min); VATi, visceral adipose tissue index (cm2/m2); SATi, subcutaneous adipose tissue index (cm2/m2); IMATi, intramuscular adipose tissue index (cm2/m2); TATi, total abdominal adipose tissue index (VAT + SAT + IMAT, cm2/m2).
  2. Multivariable models consist of: tomographic fat area index + age at CT (centered, years) + age at CT (centered, years)2 + female sex + mGFR at screening (mL/min, only in models with dependent variable mGFR after donation).