Table 1 Characteristics of the analysis population (n = 4065), stratified by SNP rs4287174 genotype.
Characteristic | All | A/A genotype | A/T genotype | T/T genotype |
|---|---|---|---|---|
Number of subjects | 4065 | 507 | 1838 | 1720 |
Women n (%) | 2122 (52%) | 272 (53%) | 946 (51.4%) | 904 (52.6%) |
Age in years mean (± SD) | 59.3 (± 7.8) | 59.5 (± 7.8) | 59.4 (± 7.8) | 59.2 (± 7.65) |
Education in years (nmiss=10) | ||||
≤ 10 n (%) | 472 (11.6%) | 60 (11.9%) | 233 (12.7%) | 179 (10.4%) |
11–13 n (%) | 2255 (55.6%) | 292 (57.9%) | 968 (52.8%) | 995 (57.9%) |
14–17 n (%) | 894 (22.1%) | 99 (19.7%) | 427 (23.3%) | 368 (21.4%) |
≥ 18 n (%) | 434 (10.7%) | 53 (10.5%) | 205 (11.2%) | 176 (10.2%) |
Income in €/month (nmiss = 263) median (Q1-Q3) | 1449 (1108–1875) | 1449 (1086–1875) | 1449 (1107–1875) | 1449 (1108–1875) |
CRP in mg/dl median (Q1-Q3) | 0.15 (0.07–0.32) | 0.11 (0.05–0.24) | 0.14 (0.07–0.29) | 0.18 (0.09–0.40) |
loge(CRP + 1) mean (± SD) | 0.22 (± 0.25) | 0.17 (± 0.19) | 0.21 (± 0.24) | 0.25 (± 0.28) |
BMI (kg/m2) (nmiss=20) Mean (± SD) | 27.88 (± 4.6) | 28.37 (± 4.83) | 27.8 (± 4.62) | 26.72 (± 4.58) |
Diabetes mellitus n (%) | 503 (12.4%) | 53 (10.5%) | 217 (11.8%) | 233 (13.5%) |
Dietary pattern index (nmiss=74) Median (Q1-Q3) | 13 (10–15) | 13 (10–15) | 13 (10–15) | 12 (10–15) |
Coronary artery calcification (nmiss=868) Mean (± SD) | 126.51 (± 357.37) | 136.98 (± 366.24) | 110,49 (± 292.34) | 140,82 (± 413.91) |
Total Cholesterol mg/dl (nmiss=1) Median (Q1-Q3) | 230 (205–255) | 230 (205–255) | 231 (204–255) | 232 (206–255) |
Current smoking n (%) | 958 (23.6%) | 120 (23.7%) | 427 (23.2%) | 411 (23.9%) |
Hypertension n (%) | 475 (11.7%) | 48 (9.5%) | 206 (11.2%) | 221 (12.8%) |
No exercise n (%) | 1971 (48.5%) | 241 (47.5%) | 893 (48.6%) | 837 (48.7%) |