Table 1 Characteristics of the analysis population (n = 4065), stratified by SNP rs4287174 genotype.

From: Socioeconomic position interacts with the genetic effect of a CRP gene common variant to influence C-reactive protein values

Characteristic

All

A/A genotype

A/T genotype

T/T genotype

Number of subjects

4065

507

1838

1720

Women n (%)

2122 (52%)

272 (53%)

946 (51.4%)

904 (52.6%)

Age in years mean (± SD)

59.3 (± 7.8)

59.5 (± 7.8)

59.4 (± 7.8)

59.2 (± 7.65)

Education in years (nmiss=10)

    

≤ 10 n (%)

472 (11.6%)

60 (11.9%)

233 (12.7%)

179 (10.4%)

11–13 n (%)

2255 (55.6%)

292 (57.9%)

968 (52.8%)

995 (57.9%)

14–17 n (%)

894 (22.1%)

99 (19.7%)

427 (23.3%)

368 (21.4%)

≥ 18 n (%)

434 (10.7%)

53 (10.5%)

205 (11.2%)

176 (10.2%)

Income in €/month (nmiss = 263) median (Q1-Q3)

1449 (1108–1875)

1449 (1086–1875)

1449 (1107–1875)

1449 (1108–1875)

CRP in mg/dl median (Q1-Q3)

0.15 (0.07–0.32)

0.11 (0.05–0.24)

0.14 (0.07–0.29)

0.18 (0.09–0.40)

loge(CRP + 1) mean (± SD)

0.22 (± 0.25)

0.17 (± 0.19)

0.21 (± 0.24)

0.25 (± 0.28)

BMI (kg/m2) (nmiss=20)

Mean (± SD)

27.88 (± 4.6)

28.37 (± 4.83)

27.8 (± 4.62)

26.72 (± 4.58)

Diabetes mellitus n (%)

503 (12.4%)

53 (10.5%)

217 (11.8%)

233 (13.5%)

Dietary pattern index (nmiss=74)

Median (Q1-Q3)

13

(10–15)

13

(10–15)

13

(10–15)

12

(10–15)

Coronary artery calcification (nmiss=868)

Mean (± SD)

126.51 (± 357.37)

136.98

(± 366.24)

110,49

(± 292.34)

140,82

(± 413.91)

Total Cholesterol mg/dl (nmiss=1)

Median (Q1-Q3)

230 (205–255)

230 (205–255)

231 (204–255)

232 (206–255)

Current smoking n (%)

958 (23.6%)

120 (23.7%)

427 (23.2%)

411 (23.9%)

Hypertension n (%)

475 (11.7%)

48 (9.5%)

206 (11.2%)

221 (12.8%)

No exercise n (%)

1971 (48.5%)

241 (47.5%)

893 (48.6%)

837 (48.7%)

  1. Legend: mean; standard deviation (SD), CRP (C-reactive Protein), log transformed CRP (logCRP), n miss:missing number in each group. T allele means the CRP risk effect allele and A the protective (reference) allele of rs4287174 genotype.