Table 3 Age- and sex- adjusted relative effect size estimates (exp(beta)) and corresponding 95% confidence intervals (95%-CI) for the interactions of rs4287174 alleles with education groups (years) and income quartiles on CRP values in separate linear regression models.

From: Socioeconomic position interacts with the genetic effect of a CRP gene common variant to influence C-reactive protein values

 

exp(ß)

95% CI

p

Education (n = 4055)

   

ß0

1.068

0.987 ; 1.157

0.104

Sex

0.985

0.969 ; 1.001

0.007

Age

1.002

1.001 ; 1.003

0.001

≤ 10y¥

1.028

0.958 ; 1.104

0.438

11-13y¥

1.005

0.951 ; 1.063

0.850

14-17y¥

0.981

0.921 ; 1.044

0.543

rs4287174§

1.005

0.970 ; 1.041

0.786

≤ 10y¥ * rs4287174§

1.056

1.005 ; 1.108

0.029

11-13y¥ * rs4287174§

1.044

1.005 ; 1.084

0.027

14-17y¥ * rs4287174§

1.043

0.999 ; 1.089

0.056

Income (n = 3802)

   

ß0

0.998

0.926 ; 1.076

0.963

Sex

1.000

0.984 ; 1.016

0.978

Age

1.002

1.001 ; 1.003

0.001

1st Quartileπ

1.055

1.001 ; 1.113

0.047

2nd Quartileπ

1.020

0.970 ; 1.072

0.438

3rd Quartileπ

1.016

0.967 ; 1.068

0.532

rs4287174§

1.044

1.018 ; 1.071

0.001

1st Quartileπ * rs4287174§

1.000

0.965 ; 1.036

0.992

2nd Quartileπ * rs4287174§

1.013

0.978 ; 1.048

0.477

3rd Quartileπ* rs4287174§

0.998

0.965 ; 1.032

0.889

  1. § included in the analysis using an additive genetic model with T as the effect allele and A as the reference allele; ¥highest education group ≥ 18y used as reference; π4th (highest) quartile was used as reference.
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