Fig. 2

A 63-year-old male diagnosed with glioblastoma. (A) T2W imaging. (B) T1W imaging. (C) Contrast-enhanced T1W imaging. (D) Dfast (×10-4mm2/s). (E) Dslow (×10-4mm2/s). (F) frac (%). (G-I) Histogram plot of Dfast, Dslow, and frac of the enhanced tumor area. The MRI examination revealed an irregular lesion in the sub-cortex of the right frontal lobe, characterized by a blurred margin. The lesion exhibited diffuse enhancement, marked in red, along with hyper-intensity on T2-weighted imaging and hypo-intensity on T1-weighted imaging. Peritumoral edema was also observed. Parametric values obtained from histogram analysis of the enhanced tumor area are as follows: Dfast: mean: 37.98, entropy: 3.19, skewness: 1.15, kurtosis: 6.60. Dslow: mean: 8.52, entropy: 3.68. skewness: 0.33, kurtosis: 3.60, frac: mean: 18.46, entropy: 3.07, skewness: 0.68, kurtosis: 5.06.