Fig. 3 | Scientific Reports

Fig. 3

From: Bi-exponential diffusion-weighted imaging for differentiating high-grade gliomas from solitary brain metastases: a VOI-based histogram analysis

Fig. 3

A 34-year-old female diagnosed with brain metastasis originating from breast cancer. (A) T2W imaging. (B) T1W imaging. (C) Contrast-enhanced T1W imaging. (D) Dfast (×10-4mm2/s). (E) Dslow (×10-4mm2/s). (F) frac (%). (G-I) Histogram plot of Dfast, Dslow, and frac of the enhanced tumor area. The MRI examination revealed an irregular lesion with a well-defined margin in the sub-cortex of the right occipital lobe. The lesion exhibited diffuse enhancement, marked in red, and appeared hyper-intense on T2-weighted imaging, hypo-intense on T1-weighted imaging, and was accompanied by peritumoral edema. Additionally, central necrosis was observed within the lesion. Parametric values obtained from histogram analysis of the enhanced tumor area are as follows: Dfast: mean: 45.38, entropy: 3.80, skewness: 0.70, kurtosis: 4.42; Dslow: mean: 8.55, entropy: 4.09, skewness: 0.47, kurtosis: 2.85; frac: mean: 25.15, entropy: 3.76, skewness: 0.49, kurtosis: 3.31.

Back to article page