Fig. 5
From: Kisspeptin is elevated in the brain after intracerebral haemorrhagic stroke
The distribution of kisspeptin immunoreactivity in relation to CD31+ vasculature. Multiplexed immunofluorescence images from cerebral tissue sections show elevated kisspeptin immunoreactivity near red blood cells in proximity to CD31+ vasculature in both intracerebral haemorrhage (ICH) and ICH with cerebral amyloid angiopathy (ICH CAA) cohorts, compared to sudden death controls (Control). Hoechst stain (nuclear marker) labelled nuclei in the DAPI channel (blue); red blood cell autofluorescence in the FITC channel (green); CD31 (vasculature endothelial marker) labelled in the Cy5 channel (magenta), and KISS (kisspeptin marker) labelled in the Cy3 channel (red); and a composite of all four fluorescence channels. Scale bars, 100 µm.
