Table 2 Comparative statistics of anti-MOG with demographic and clinical parameters.
Anti-MOG | ||||||||
|---|---|---|---|---|---|---|---|---|
Negative (n = 37) | Positive (n = 3) | P-value | ||||||
Age (years) | Range | 10 | - | 62 | 12 | - | 40 | 0.696 |
Mean ± SD | 29.73 | ± | 12.89 | 26.66 | ± | 14.04 | ||
N | (%) | N | (%) | P-value | ||||
Gender | Male | 12 | (32.43) | 3 | (100) | 0.232 | ||
Female | 25 | (67.57) | 0 | (0) | ||||
Risk factors | Smoking | 3 | (8.11) | 0 | (0.00) | 0.608 | ||
FH of MS | 0 | (0.00) | 0 | (0.00) | - | |||
FH of Consanguinity | 13 | (35.14) | 0 | (0.00) | 0.211 | |||
FH of Autoimmune disease | 3 | (8.11) | 0 | (0.00) | 0.608 | |||
Relapses | No | 25 | (67.57) | 2 | (66.67) | 0.974 | ||
Yes | 12 | (32.43) | 1 | (33.33) | ||||
Number of attacks | One | 6 | (50.00) | 1 | (100.0)0) | 0.968 | ||
Two | 2 | (16.67) | 0 | (0.00) | ||||
Four | 1 | (8.33) | 0 | (0.00) | ||||
Five | 1 | (8.33) | 0 | (0.00) | ||||
Six | 1 | (8.33) | 0 | (0.00) | ||||
Eight | 1 | (8.33) | 0 | (0.00) | ||||
Type of attacks | Cranial nerves(optic) | 8 | (66.67) | 1 | (100.00) | 0.488 | ||
Motor | 4 | (33.33) | 0 | (0.00) | ||||
Treatment during attack | Pulse steroids | 7 | (58.33) | 1 | (100.00) | 0.713 | ||
IVIG | 4 | (33.33) | 0 | (0.00) | ||||
Mixed | 1 | (8.33) | 0 | (0.00) | ||||
Maintenance treatment | Methotrexate | 2 | (5.41) | 0 | (0.00) | 0.826 | ||
Vitamins &Iron | 21 | (56.76) | 3 | (100.00) | ||||
Oral steroids | 3 | (8.11) | 0 | (0.00) | ||||
Azathioprine | 6 | (16.22) | 0 | (0.00) | ||||
MabThera™/Rituximab | 5 | (13.51) | 0 | (0.00) | ||||