Fig. 6 | Scientific Reports

Fig. 6

From: Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma

Fig. 6

Synergy between IAP antagonist (BV6) and AKT inhibitor (ALM301) in OAC organoid models. (A) CellTiter Glo viability of OAC organoids following ALM301 /BV6 combination treatment. Significant interaction by 2-Way ANOVA is represented as P value < 0.05*, 0.01** and 0.001*** (B) ALM301/BV6 synergy analysis using Loewe and BLISS methods where positive scores represent synergy, negative scores represent antagonism and scores of 0 represent an additive effect.

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