Table 1 Localization of ITK-SYK in different cell compartments in steady state and following activation(from 4 different experiments).
Number of cells | Nuclear | Cytoplasmic | Membrane | Cytoplasmic/Nuclear | Nuclear/Membrane |
|---|---|---|---|---|---|
ITK-SYK (Steady state) | |||||
 500 | 17 | 343 | 72 | 61 | 7 |
 500 | 22 | 317 | 93 | 57 | 11 |
 500 | 14 | 298 | 108 | 72 | 8 |
 500 | 12 | 346 | 74 | 64 | 4 |
 2000 | 65 | 1304 | 347 | 254 | 30 |
 Percentage | 3.1% | 66% | 16.7% | 12.5% | 1.5% |
ITK-SYK (Activated) | |||||
 500 | 232 | 42 | 94 | 88 | 44 |
 500 | 177 | 53 | 108 | 103 | 59 |
 500 | 193 | 49 | 88 | 107 | 63 |
 500 | 214 | 52 | 91 | 93 | 50 |
 2000 | 816 | 196 | 381 | 391 | 216 |
 Percentage | 40.7% | 10.1% | 18.5% | 19.6% | 10.9% |
