Fig. 3 | Scientific Reports

Fig. 3

From: Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis

Fig. 3

ARS estimation and stratification analysis in KIRC patients. (A) Box plot showing the differences in ssGSEA ARS between KIRC and normal samples by Wilcoxon test. Box plot comparing ssGSEA ARS between (B) Stage, (C) TNM.T, (D) TNM.M., (E) KIRC patients were divided into the low-ARS and high-ARS groups using the surv_cutpoint function. (F) KM survival curves of the OS for KIRC patients in the high-ARS and low-ARS groups. (G) Comparison of TMB between the high-ARS and low-ARS groups. (H) Comparison of the immune checkpoint between the high-ARS and low-ARS groups. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. TMB: Tumor mutation burden. ADME: Absorption, distribution, metabolism and excretion.

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