Fig. 4
From: Tracking the genetic diversity of SARS-CoV-2 variants in Nicaragua throughout the COVID-19 pandemic

Number of mutations in lineages circulating in Nicaragua. Heatmap indicates the number of times a specific amino acid (aa) substitution (y-axis) was observed among our sequences within a given lineage (x-axis). Lineages are named using Pangolin nomenclature and their WHO Greek-letter designation if they have one. Substitution nomenclature follows standard practice: gene: original aa state, gene position, new aa state.