Fig. 4 | Scientific Reports

Fig. 4

From: A disintegrin and metallopeptidase domain (ADAM) 12, ADAM 17 mRNA and ADAM10 protein hold potential as biomarkers for detection of early gastric cancer

Fig. 4

ADAM and MICA mRNA expression in the combined sets of plasma samples of patients with early gastric cancer and healthy controls. mRNA expression levels of (A) ADAM9 (p = 0.858), (B) ADAM10 (p = 0.803), (C) ADAM12 (p = 0.0007), (D) ADAM17 (p < 0.0001), and (E) MICA (p = 0.319) were examined using qPCR in plasma samples obtained from early gastric cancer (case, n = 27, shown in red) and healthy controls (control, n = 30, shown in blue). The data were normalized to an internal control (GAPDH) and presented as relative expression. *p < 0.05, **p < 0.005, ***p < 0.001, ****p < 0.0001, ns. not specific; t-test or Mann–Whitney U test.

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