Fig. 1
From: 5,7-Dihydroxyflavone acts on eNOS to achieve hypotensive effects in spontaneously hypertensive rats
The network pharmacological analysis of chrysin-target interactions. (a) There are five kinds of labels including Chrysin compound (rotundity, yellow), drug targets (rectangle, blue), KEGG pathways (oval, green), OMIM disease (rectangle, grey). A view of the chrysin effects and actives. (b) The 2D and 3D structure diagram of conformation 1 Chrysin-eNOS complex, the black labels are binding sites. (c) The 2D and 3D structure diagram of conformation 2 Chrysin-eNOS complex, the black labels are binding sites. (d) The molecular dynamic simulation RMSD value for 100 ns of conformation 1 Chrysin-eNOS complex. (e) The molecular dynamic simulation RMSD value for 100 ns of conformation 2 Chrysin-eNOS complex.
