Fig. 3 | Scientific Reports

Fig. 3

From: lncRNA CHAF1B-2 contributes to the tumorigenesis of gastric cancer by activating the Wnt/β-catenin pathway

Fig. 3

Lnc-CHAF1B-2 enhanced the malignant proliferation of gastric cancer cells. (A) The results of the EdU assay revealed that knockdown of lnc-CHAF1B-2 reduced the malignant proliferation of gastric cancer cells, whereas overexpression of lnc-CHAF1B-2 enhanced their malignant proliferation (scale bar, 500 μm). (B) Flow cytometry images of the cell cycle in gastric cancer cells in which lnc-CHAF1B-2 was knocked down or overexpressed. (C) Flow cytometry images of apoptosis in gastric cancer cells in which lnc-CHAF1B-2 was knocked down or overexpressed. NC: blank control group, Control: negative control, si-lnc-CHAF1B-2:small interfering RNA1, Vector: empty vector, lnc-CHAF1B-2-OE: lnc-CHAF1B-2 overexpression.*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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