Fig. 3

Volcano plot of protein abundance association with gestational age. Shown are -log₁₀ of the FDR adjusted P values and betas from linear regression models for a unit increase in continuous gestational age term on a standard deviation increase in protein abundance for a given protein adjusted for sex, preeclampsia, labor route of delivery. Colors show direction of linear associations (positive [blue] indicates increasing GA associated with increasing protein abundance and negative [red] indicates decreasing GA associated with decreasing protein abundance). Seventy proteins were found to be significantly associated with gestational age in adjusted models. Proteins with FDR adjusted p < 0.0001 are labelled. The full list of proteins with FDR adjusted p < 0.05 can be found in Supplementary Table 1.