Fig. 1 | Scientific Reports

Fig. 1

From: Clinical outcomes of endocrine and other disorders induced by immune checkpoint inhibitors in Japanese patients

Fig. 1

(A) Age at the first ICI administration. (B) Number of times ICI was administered during the observation period. (C) Stage of malignancy at the time of the first dose of ICI. (D) Frequency of irAEs for each ICI used. Non-irAE, subjects without irAE (n = 285); E-irAE, those having only endocrine-related irAE (n = 112); O-irAE, those having other irAE (n = 103), EO-irAE, those having both endocrine-related and other irAE (n = 56); ME-irAE, those having multiple endocrine-related irAE (n = 15). Data for age and number of times ICI was administered represent interquartile range (IQR), and error bars represent 90% tiles. Kruskal-Wallis test or chi-square test was used for analysis. ***p < 0.001 vs. non-irAE.

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