Fig. 2 | Scientific Reports

Fig. 2

From: Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies

Fig. 2

Differentially glomerular expression profiles of complement proteins in patients with diabetic kidney disease, compared to normal controls and arterionephrosclerosis. In the heatmap, each row represents one complement protein, and each column corresponds to one patient’s dataset. Normalized relative abundances of glomerular complement proteins are depicted by a pseudo-color scale, with red indicating a higher level of protein expression, white indicating an equal level, and blue indicating a lower expression level compared with mean protein abundance of each sample. The dendrogram displays the outcome of unsupervised hierarchical clustering analysis, placing similar proteome profile values near to each other. DKD, diabetic kidney disease; NC, normal controls; HTN, hypertension; CFB, complement factor B; CFH, complement factor H; CFHR, complement factor H related protein.

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