Table 2 Associations between TyG index, HOMA-IR, QUICKI and MAFLD in the logistic multiple regression model.

From: Association between TyG related parameters and metabolic dysfunction associated fatty liver disease among nondiabetic individuals

Variable

Unadjuseted

Model 1

Model 2

Model 3

Model 4

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

TyG

5.421 (3.831–7.671)*

5.296 (3.655–7.674)*

3.732 (2.499–5.575)*

3.721 (2.482–5.576)*

3.971 (1.418–11.116)*

TyG index quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

2.854 (1.496–5.447)*

2.883 (1.503–5.533)*

2.283 (1.145–4.552)*

2.358 (1.178–4.720)*

2.098 (1.027–4.282)*

 Q3 (n = 236)

5.167 (2.791–9.567)*

5.102 (2.718–9.579)*

3.043 (1.562–5.926)*

3.057 (1.564–5.975)*

2.301 (1.106–4.786)*

 Q4 (n = 237)

11.180 (6.143–20.346)*

11.11 (5.948–20.752)*

6.428 (3.335–12.393)*

6.562 (3.381–12.737)*

3.235 (1.280–8.173)*

TyG-WHtR

4.155 (3.317–5.204)*

4.609 (3.616–5.874)*

3.204 (2.343–4.381)*

3.235 (2.353–4.447)*

2.355 (1.582–3.506)*

TyG-WHtR quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

1.177 (0.533–2.602)

1.036 (0.463–2.321)

0.769 (0.338–1.749)

0.753 (0.33–1.718)

0.607 (0.26–1.419)

 Q3 (n = 236)

5.146 (2.664–9.939)*

4.743 (2.394–9.399)*

2.726 (1.317–5.64)*

2.668 (1.287–5.529)*

1.805 (0.821–3.97)

 Q4 (n = 237)

22.296 (11.821–42.053)*

23.182 (12.031–44.671)*

8.63 (4.032–18.469)*

8.66 (4.029–18.614)*

4.699 (1.95–11.321)*

TyG-WC

1.009 (1.008–1.011)*

1.009 (1.008–1.011)*

1.008 (1.006–1.010)*

1.008 (1.006–1.01)*

1.006 (1.003–1.008)*

TyG-WC quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

3.226 (1.419–7.338)*

2.867 (1.249–6.582)*

1.843 (0.783–4.334)

1.802 (0.764–4.247)

1.398 (0.581–3.365)

 Q3 (n = 236)

7.468 (3.451–16.161)*

6.475 (2.937–14.277)*

3.190 (1.381–7.366)*

3.154 (1.365–7.292)*

1.998 (0.82–4.866)

 Q4 (n = 237)

31.808 (15.029–67.319)*

29.357 (13.729–62.776)*

8.863 (3.675–21.373)*

8.758 (3.624–21.161)*

3.659 (1.347–9.938)*

TyG-BMI

1.023 (1.019–1.026)*

1.025 (1.021–1.029)*

1.028 (1.021–1.036)*

1.029 (1.021–1.036)*

1.022 (1.012–1.032)*

TyG-BMI quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

2.335 (1.041–5.241)*

1.96 (0.865–4.439)

1.449 (0.628–3.343)

1.463 (0.633–3.381)

1.075 (0.454–2.546)

 Q3 (n = 236)

7.305 (3.511–15.200)*

5.929 (2.807–12.523)*

3.421 (1.529–7.657)*

3.455 (1.541–7.745)*

2.090 (0.880–4.961)*

 Q4 (n = 237)

27.677 (13.566–56.467)*

26.809 (13.042–55.108)*

9.623 (3.901–23.738)*

9.847 (3.983–24.344)*

4.14 (1.481–11.572)*

HOMA.IR

1.712 (1.531–1.914)*

1.762 (1.567–1.981)*

1.409 (1.249–1.589)*

1.42 (1.258–1.603)*

1.298 (1.137–1.481)*

HOMA.IR quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

1.595 (0.841–3.025)

1.649 (0.863–3.15)

1.384 (0.713–2.686)

1.388 (0.714–2.697)

1.318 (0.655–2.649)

 Q3 (n = 236)

3.731 (2.088–6.667)*

4.263 (2.356–7.714)*

2.463 (1.319–4.601)*

2.452 (1.311–4.586)*

2.202 (1.140–4.253)*

 Q4 (n = 237)

11.158 (6.402–19.448)*

12.657 (7.141–22.434)*

5.146 (2.785–9.509)*

5.322 (2.874–9.855)*

3.813 (1.935–7.512)*

log2QUICKI

0.001 (0–0.003)*

0.015 (0.003–0.080)*

0.006 (0.001–0.026)*

0.006 (0.001–0.028)*

0 (0–0.002)*

QUICKI quantiles

 Q1 (n = 236)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (n = 236)

0.332 (0.223–0.494)*

0.335 (0.222–0.506)*

0.473 (0.303–0.738)*

0.454 (0.289–0.712)*

0.574 (0.354–0.931)*

 Q3 (n = 236)

0.142 (0.088–0.229)*

0.129 (0.079–0.213)*

0.267 (0.156–0.455)*

0.258 (0.150–0.442)*

0.343 (0.192–0.614)*

 Q4 (n = 237)

0.089 (0.051–0.154)*

0.078 (0.044–0.138)*

0.192 (0.104–0.355)*

0.185 (0.100–0.343)*

0.259 (0.131–0.511)*

  1. Model 1: adjusted for sociodemographic variables (gender, age, race and ethnicity and marital status). Model 2: adjusted for model 1 + hip circumference. Model 3: adjusted for model 2 + hypertention, physical activity and smoking status. Model 4: adjusted for model 3 + SBP, DBP, HDL, LDL, Tc, CRP, ALT, AST, BUN, GGT and uric acid. OR, odds ratio; 95% CI, 95% confidence interval. *P < 0.05.
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