Table 1 Key demographic and clinical characteristics.
From: Patients with dementia with Lewy bodies display a signature alteration of their cognitive connectome
DLB (N = 104) | HC (N = 3703) | AD (N = 1985) | DLB vs. HC | DLB vs. AD | ||
|---|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | Mean (SD) | p-value | p-value | ||
Age, years min-max | 71.9 (8.5) 45–88 | 72.2 (9.2) 45–101 | 73.7 (9.9) 45–103 | 0.7 | 0.1 | |
Sex, men (%) | 86% | 43% | 47% | < 0.001 | < 0.001 | |
Education, years | 16.3 (3.1) | 16.0 (2.9) | 15.4 (3.0) | 0.3 | < 0.01 | |
CDR-total, median (interquartile range) | 1 (0.5-1) | 0 (0–0) | 1 (0.5-1) | < 0.001 | 0.2 | |
Cognitive fluctuations, present (%) | 60% | 1% | 4% | < 0.001 | < 0.001 | |
Visual hallucinations, present (%) | 43% | 1% | 4% | < 0.001 | < 0.001 | |
Probable RBD, present (%) | 65% | 1% | 3% | < 0.001 | < 0.001 | |
Parkinsonian signs, present (%) | 82% | 3% | 11% | < 0.001 | < 0.001 | |
Cognitive domains | ||||||
Visuoconstructive functions | -1.8 (1.8) | 0 (0.8) | -1.6 (1.9) | < 0.001 | 0.1 | |
Visual and verbal episodic memory | -1.5 (0.9) | 0 (0.6) | -2.1 (0.9) | < 0.001 | < 0.001 | |
Executive functions | -0.9 (0.8) | 0 (0.5) | -0.9 (0.7) | < 0.001 | 0.2 | |
Processing speed/attention | -2.1 (1.6) | 0 (0.7) | -1.7 (1.7) | < 0.001 | < 0.01 | |
Language | -1 (1.1) | 0 (0.8) | -1.5 (1.6) | < 0.001 | < 0.001 | |
Orientation | -3.1 (4.2) | 0 (1) | -6.9 (5.5) | < 0.001 | < 0.001 | |
