Table 4 ROC curve and corresponding optimal cutoff point of vessel density for discriminating the presence of DR in DM patients.

From: Vulnerable parafoveal microcirculation quadrant in patients with type 2 diabetes mellitus

Region

AUC

95% CI

p value

Optimal cutoff point (%)

Sensitivity (%)

Specificity (%)

Parafoveal superficial VD

0.581

(0.428–0.723)

0.454

≤ 41.96

36.4

83.3

Sectoral VD of parafoveal superficial region

T

0.601

(0.448–0.741)

0.318

≤ 39.09

27.3

97.2

S

0.639

(0.486–0.774)

0.152

≤ 50.09

90.9

38.9

N

0.505

(0.355–0.654)

0.964

≤ 48.68

54.6

22.2

I

0.566

(0.413–0.710)

0.532

≤ 42.89

45.5

72.2

Parafoveal deep VD

0.687

(0.535–0.814)

0.048*

≤ 45.81

36.4

94.4

Sectoral VD of parafoveal deep region

T

0.697

(0.546–0.822)

0.035*

≤ 51.86

81.8

52.8

S

0.631

(0.478–0.767)

0.199

≤ 45.54

36.4

88.9

N

0.600

(0.447–0.740)

0.283

≤ 51.19

63.6

58.3

I

0.682

(0.530–0.810)

0.050

≤ 50.75

90.9

41.7

  1. ROC Receiver operating characteristic, AUC Area under the ROC curve, VD vessel density, OR odds ratio, CI confidence interval, T temporal, S superior, N nasal, I inferior.
  2. *p value less than 0.05.