Fig. 7

Irisin alleviates TBI-induced damage by regulating AMPK/MerTK to inhibit apoptosis and by suppressing SYK/ROS/inflammatory signaling pathways. (A) ELISA detection of IL-1β and TNFα levels in the seven groups; (B) ELISA detection of MDA, GSH, and SOD levels in the seven groups; (C) Flow cytometry detection of apoptosis in BV2 cells in the seven groups. Data are expressed as the mean ± standard deviation. **P<0.01; *P<0.05.