Table 3 Association between biological aging and the risk of all-cause mortality among lung cancer patients.

From: Associations of biological aging with the morbidity and all-cause mortality of patients with lung cancer

Ā 

Crude model

Model 1

Model 2

HR

CI

P value

HR

CI

P value

HR

CI

P value

PhenoAge acceleration

Ā Continuous

1.1

1.04ā€“1.17

<ā€‰0.001

1.09

1.03ā€“1.15

0.002

1.12

1.04ā€“1.20

0.003

Ā Q1

Reference

Ā Ā 

Reference

Ā Ā 

Reference

Ā Ā 

Ā Q2

2.36

0.92ā€“6.05

0.073

1.95

0.73ā€“5.22

0.185

8.42

1.26ā€“56.40

0.028

Ā Q3

2.93

1.12ā€“7.70

0.029

2.37

0.80ā€“7.03

0.121

7.07

1.14ā€“43.82

0.036

Ā Q4

4.9

1.76ā€“13.67

0.002

3.44

1.24ā€“9.54

0.018

11.82

1.48ā€“94.35

0.02

Ā P for trend

Ā Ā 

0.002

Ā Ā 

0.019

Ā Ā 

0.019

Nonaging

Reference

Ā Ā 

Reference

Ā Ā 

Reference

Ā Ā 

Aging

2.18

1.13ā€“4.22

0.02

1.81

0.88ā€“3.73

0.105

3.19

1.28ā€“7.94

0.013

  1. Crude model: nonadjusted model; Model 1: adjusted for age, sex, race; Model 2: adjusted for covariates of Model 1, and smoking status, drinking status, education level, body mass index, history of emphysema, and family income-to-poverty ratio. Nonaging: PhenoAge accelerationā€‰ā‰¤ā€‰0. Aging: PhenoAge accelerationā€‰>ā€‰0. Abbreviations: Q, quartile.
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