Fig. 1
From: Enhancing outcomes in Langendorff-perfused rodent hearts through perfusion parameter optimization
Viability markers of hearts perfused with or without pRBCs at low (30–35 mmHg) and higher (60–80 mmHg) pressures. Oxygen uptake rate (A), lactate accumulation over perfusion time (B), vascular resistance (C), adenylated energy charge (D), representative H&E images of coronary arteries (E-H). Scale bar 50 μm. Data presented as median ± interquartile range. Wilcoxon/Kruskal-Wallis Test with Dunn post-hoc analysis on non-parametric medians. Repeated measures two-way ANOVA and Tukey-Kramer HSD post-hoc analysis on standard least squares means. * = p < 0.05, ** = p ≤ 0.01, **** = p ≤ 0.0001.
