Fig. 6

Influence of pharmacological treatment in cardiac functional markers. Heart rate, obtained from intraventricular balloon recordings. Solid line indicates median of the experimental replicates, the shaded area indicates interquartile range (A), maximum systolic pressure over time, denoted as left ventricular pulse pressure (LVPP). Solid line indicates median of the experimental replicates, the shaded area indicates interquartile range (B), area under the curve (AUC) of heart rate data for every hour of perfusion (C), the area under the LVPP curve (AUC) for every hour of perfusion (D), cardiac muscle contractility quantified from the maximum derivative of the pressure pulse (E), cardiac muscle relaxation quantified from the minimum derivative of the pressure pulse (F). Repeated measures two-way ANOVA and Tukey-Kramer HSD post-hoc analysis on standard least squares means. All data are expressed as median ± interquartile range.   * = p < 0.05, ** = p ≤ 0.01