Table 4 List of the most significant SMPDB pathways.

From: Urine metabolite profiling in Indian males exposed to high-altitude: a longitudinal pilot study

S. No

Metabolite set

Total

Hits

Expect

p value

Holm P

FDR

1

Tryptophan metabolism

59

7

2.18

0.004

0.429

0.429

2

Catecholamine biosynthesis

20

3

0.74

0.034

1

1

3

Arginine and proline metabolism

52

5

1.92

0.038

1

1

4

Carnitine synthesis

22

3

0.81

0.044

1

1

  1. SMPDB Pathway analysis was performed using MetaboAnalyst 6.0. to identify pathways that were significantly altered after HA exposure. Here, Total: Total number of compounds in the pathways; Hits: Number of compound matched from our data; p Value: The original p value calculated from pathway analysis; Holm p: p Values adjusted by the Holm–Bonferroni method; FDR, false discovery rate.
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