Fig. 4

HPC activates BDNF/TrkB/PLCγ signaling in the hippocampus of restraint stress model mice. The western blot analyzed phosphorylated and total proteins expression of TrkB (A), PLCγ (B), and CREB (C) in mouse hippocampus. Data presented as mean ± SEM, n = 6. * represents a statistically significant compared to the control group, with P < 0.05. # represents a statistically significant compared to the restraint stress model, with P < 0.05.