Fig. 5 | Scientific Reports

Fig. 5

From: Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

Fig. 5

HPC remedies dendritic complexity and spine density of hippocampal DG neurons in restraint stress model mice. (A) Representative images of Golgi staining and traces of Sholl analysis for hippocampal DG neurons and their dendritic spines. (B) The density of total spine and mushroom, stubby, thin spines in hippocampal DG neurons of mice. (C) The number of dendritic intersections for Sholl analysis in hippocampal DG neurons of mice. (D) The western blot detected protein expression of PSD-95 in mouse hippocampus. Data presented as mean ± SEM, n = 8 for Golgi staining, n = 6 for western blot. * represents a statistically significant compared to the control group, with P < 0.05. # represents a statistically significant compared to the restraint stress model, with P < 0.05.

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