Fig. 10 | Scientific Reports

Fig. 10

From: Designing a multi-epitope vaccine against African swine fever virus using immunoinformatics approach

Fig. 10

(a) Immunoglobulin production (coloured peak) in response to antigen (black peak); (b) B lymphocytes: total count, memory cells, and sub-divided in isotypes IgM, IgG1 and IgG2; (c) B Lymphocyte population per entity state; (d) Plasma B lymphocytes count sub-divided per isotype (IgM, IgG1 and IgG2); (e) CD4 T-helper lymphocytes and memory count; (f) CD4 T-helper lymphocytes count sub-divided per entity-state; (g) CD4 T-regulatory lymphocytes count comprising of total, memory and per entity state counts; (h) CD8 T-cytotoxic lymphocytes count showing total and memory; (i) CD8 T-cytotoxic lymphocytes count per entity-state; (j) Natural Killer cells total count; (k) Dendritic cells count per state of antigen presentation; (l) Macrophages: Total count, internalized, presenting on MHC class-II, active and resting macrophages; (m) Epithelial cells: Total count broken down to active, virus-infected and presenting on class-I MHC molecule; (n) Cytokines: Concentration of cytokines and interleukins with IL2 level and Simpson index (D) in the inset plot.

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