Fig. 2 | Scientific Reports

Fig. 2

From: Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy

Fig. 2

The Bufei Yishen formula inhibits inflammation, oxidative stress, and protease expression in COPD rats. (A) Expression of IL-1β, IL-6 and TNF-α in lung tissue were detected using the immunohistochemical method and quantified as their integral optical density (IOD). (B) The expression of SOD2, MMP-2, and MMP-9 were detected by using immunohistochemical method and quantified as their integral optical density (IOD). Values are expressed as the mean ± SEM (n = 6), *P < 0.05, **P < 0.01 compared with the control group; #P < 0.05, ##P < 0.01 compared with the model group.

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