Fig. 4

Visualization of significant differentially expressed genes (DEGs) and their enrichment in ontology terms.

The circos plot displays selected Gene Ontology (GO) terms associated with DEGs in porcine anterior pituitary cells, whose expression was altered by visfatin (p < 0.05, log₂FC>|0.56|). The colours of the lines represent different GO terms, while the bars corresponding to gene symbols indicate the ratio of upregulated to downregulated genes. Red bars indicate GO terms with predominantly upregulated DEGs, while blue bars indicate those with predominantly downregulated DEGs.