Fig. 2
From: Piezo1 activation protects against sepsis-induced myocardial dysfunction in a pilot study
Piezo1 agonist Yoda1 ameliorated cardiac dysfunction in SIMD mice. Mice were pretreated with Yoda1 1 h before LPS (15 mg/kg) administration (A) Representative M-mode echocardiographic images 12 h post-LPS injection. Scale bar = 100 ms/2 mm. (B-C) Quantitative analysis of LVEF% and LVFS%. (D) Quantitative analysis of Heart rate. (E) Plasma cTnT levels. (F) Representative HE stained heart sections. Scale bar = 50 μm. Data were presented as mean ± SEM. P < 0.05 was considered statistically significant.
