Table 3 Comparison of the effect of different MAT, AMB, NCMAT, and NCAMB concentrations with and without light on the average number of intra-macrophage amastigotes compared to the untreated control group (UC).

From: The synergistic anti-leishmanial effect of photodynamic therapy employing chemotherapy-mediated nanocomposites

Concentration

(µg/ml)

FNC

MAT

AMB

NCMAT

NCAMB

MAT + L

AMB + L

NCMAT + L

NCAMB + L

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

0 (UC)

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

69.4 ± 0.8

NR

25

65.1 ± 0.6

0.37

48.1 ± 1.2

< 0.001

50.1 ± 1.5

< 0.001

44.6 ± 0.8

< 0.001

46.1 ± 1.1

< 0.001

48.5 ± 1.2

< 0.001

50.3 ± 1.3

< 0.001

40.4 ± 1.3

< 0.001

45.1 ± 1.2

< 0.001

50

62.1 ± 1.0

0.86

40.6 ± 0.9

< 0.001

45.1 ± 1.4

< 0.001

37. 2 ± 0.7

< 0.001

31.3 ± 0.7

< 0.001

39.2 ± 0.6

< 0.001

40.1 ± 0.8

< 0.001

36.1 ± 0.7

< 0.001

38.2 ± 0.8

< 0.001

100

58.9 ± 0.9

0.31

35.1 ± 1.4

< 0.001

37.2 ± 0.9

< 0.001

23.4 ± 1.2

< 0.001

27.4 ± 0.4

< 0.001

25.3 ± 0.8

< 0.001

29.8 ± 0.9

< 0.001

12.3 ± 0.4

< 0.001

17.8 ± 0.3

< 0.001

200

52.4 ± 0.7

< 0.001

12.3 ± 0.2

< 0.001

15.3 ± 0.7

< 0.001

8.6 ± 0.2

< 0.001

10.2 ± 0.1

< 0.001

9.2 ± 0.3

< 0.001

11.7 ± 0.4

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

400

48.1 ± 0.8

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001

0.0 ± 0.0

< 0.001