Table 4 Identification of ATR-FTIR bands in Candida species35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50.
From: ATR-FTIR spectroscopic markers indicating drug resistance in selected Candida strains
Band (cm−1) or band ratio (cm−1/cm−1) | Assignment* | Origin/characteristics | |||
|---|---|---|---|---|---|
Candida albicans | Candida glabrata | Candida dubliniensis | |||
2958 | 2959 | 2958 | vas(CH3) | Lipids | |
2918 | 2918 | 2918 | vas(CH2) | ||
2873 | 2872 | 2873 | vs(CH3) | ||
2850 | 2850 | 2850 | vs(CH2) | ||
1745 | 1742 | 1745 | v(C=O) | Lipids, phospholipids, esters | |
1716 | 1716 | 1717 | |||
1683 | 1688 | 1684 | v(C=O), δ(NH) | AI | Amide I proteins, antiparallel β-sheet and β-turn |
1655 | 1655 | 1656 | Amide I proteins (peak), α-helix | ||
1635 | 1637 | 1637 | Amide I proteins, β-sheet | ||
1545 | 1544 | 1543 | δ(NH), v(CN) | AII | Amide II proteins |
1515 | 1515 | 1515 | |||
1495 | 1497 | 1496 | |||
1467 | 1467 | 1467 | δ(CH2), δ(CH3) | 1360–1480 cm−1 | Lipids and proteins |
1454 | 1454 | 1454 | |||
1438 | 1439 | 1439 | |||
1413 | 1414 | 1412 | |||
1402 | 1401 | 1401 | |||
1368 | 1367 | 1367 | |||
1342 | 1338 | 1340 | δ (CH2) | Phospholipids and amino acids | |
1300 | 1304 | 1300 | δ(NH) | Amide III proteins | |
1240 | 1240 | 1240 | |||
1201 | 1202 | 1201 | vas(PO2-) | Phosphomannan | |
1155 | 1154 | 1154 | C–O–C | β(1 → 3) glucan | |
1125 | 1126 | 1124 | v(CO), v(CC) | α-glucan, RNA | |
1105 | 1104 | 1105 | v(CO), v(CC), v(COC) | Glycogen and β(1 → 3) glucan | |
1077 | 1079 | 1078 | vs(PO2-), v(CO), v(CC), δ(COH) | Glycogen, phosphomannan, DNA | |
1043 | 1045 | 1044 | v(CO), v(OH) | Glycogen, mannan | |
1021 | 1022 | 1021 | v(CO) | Glycogen | |
996 | 995 | 995 | v(CC), δ(CO) | β(1 → 6) glucan | |
966 | 963 | 964 | v(CC), δ(CO) | Mannan | |
919 | 916 | 922 | v(CC), δ(CO) | Glucan, mannan | |
885 | 889 | 887 | |||
809 | 812 | 810 | δ (CH) | Glucan | |
779 | 779 | 779 | |||
762 | 762 | 761 | |||
719 | 719 | - | |||
2918/2958 | 2918/2959 | 2918/2958 | vas(CH2)/vas(CH3) | Changes in lipid chain length, branching and/or saturation level | |
2850/2873 | 2850/2872 | 2850/2873 | vs(CH2)/vs(CH3) | ||
AII/AI | AII/AI | AII/AI | Amide II/Amide I | Changes in protein structure | |
1635/1655 | 1637/1655 | 1637/1656 | β-sheet/α-helix | Changes in secondary structure of proteins | |
1125/1077 | 1126/1079 | 1124/1078 | RNA/DNA | Changes in gene expression | |
