Fig. 4

Electromagnetic waves destabilize SARS-CoV-2 Spike. (A) SC2-VLPs were produced, collected, and either unexposed or exposed to 3.1 or 5.9 GHz electromagnetic waves for 8 min. SC2-VLPs were either subjected to an ELISA to measure binding to antibodies targeting the Spike Subunit 1 receptor-binding domain (S1RBD) or pelleted and probed for Spike (S), Nucleocapsid (N), Membrane (M), and Envelope (E) by western blot. Created in https://BioRender.com. (B) Spike (S1RBD) ELISA. Data represent +/- SD of 2 independent experiments performed in quadruplicate, except for one condition (3.1 GHz) that was analyzed once in quadruplicate and once in triplicate. P-values indicate one-way ANOVA tests of treated compared to untreated samples. (C) Western blot depicting Spike (S), Nucleocapsid (N), Membrane (M), and Envelope (E) within pelleted virus particles. The image is representative of two independent experiments.