Table 1 Baseline characteristics of the study population.
Variable | Total (n = 120) | Non-severe PH (n = 35) | Severe PH (n = 85) | P- value |
|---|---|---|---|---|
Age, years | 57.5 (48.3–64.0) | 57.0 (44.0–62.0) | 57.3 ± 10.3 | 0.139 |
Male | 78 (65.0) | 21 (60.0) | 57 (67.1) | 0.461 |
Etiology | 0.020 | |||
Viral hepatitis | 48 (40.0) | 16 (45.7) | 32 (37.7) | |
HBV | 40 (33.3) | 14 (40.0) | 26 (30.6) | |
HCV | 8 (6.7) | 2 (5.7) | 6 (7.1) | |
Alcohol-related | 33 (27.5) | 3 (8.6) | 30 (35.3) | |
Other | 39 (32.5) | 15 (42.9) | 23 (27.1) | |
Laboratory parameters | ||||
Platelets,×109/L | 73.5 (50.0–98.8) | 85.0 (52.0–125.0) | 68.0 (49.5–91.0) | 0.065 |
Hemoglobin, g/L | 102.0 ± 29.4 | 124.0 (85.0–133.0) | 97.5 ± 27.5 | 0.007 |
INR | 1.3 (1.1–1.4) | 1.2 (1.1–1.3) | 1.3 (1.2–1.4) | 0.008 |
Albumin, g/L | 35.5 ± 6.1 | 38.7 ± 6.0 | 34.1 ± 5.6 | < 0.001 |
ALT, U/L | 20.0 (14.0–28.0) | 22.0 (16.0–38.0) | 20.0(13.0–26.0) | 0.227 |
AST, U/L | 30.0 (23.0–41.0) | 28.0 (21.0–39.0) | 32.0 (23.0–41.0) | 0.274 |
Bilirubin, µmol/L | 23.7 (17.2–40.6) | 21.2 (15.8–35.2) | 25.2 (17.3–42.2) | 0.299 |
Urea, mmol/L | 4.9 (3.8–6.9) | 4.8 (3.9–5.5) | 5.1 (3.8–7.1) | 0.448 |
Creatinine, µmol/L | 63.0 (55.0–77.8) | 63.0 (55.0–76.0) | 63.0 (53.5–80.5) | 0.968 |
HVPG, mmHg | 19.0 (15.0–22.0) | 10.0 (8.0–14.0) | 21.0 (18.5–23.0) | < 0.001 |
MELD score | 12.0(6.0–12.0) | 12.0 (12.0–12.0) | 12.0 (6.0–12.0) | 0.045 |
Child-Pugh grade | 0.068 | |||
A (scores 5–6) | 48 (40.0) | 19 (54.3) | 29 (34.1) | |
B (scores 7–9) | 57 (47.5) | 15 (42.8) | 42 (49.4) | |
C (scores 10–15) | 15 (12.5) | 1 (2.9) | 14 (16.5) | |
Spleen volume, cm3 | 719.24 (504.35–952.98) | 615.85 ± 308.59 | 779.76 (567.96–1041.13) | 0.005 |
Endoscopic parameters | ||||
bleeding risk of esophageal varices | 0.003 | |||
low risk | 32 (28.57) | 16 (48.48) | 16 (20.25) | |
high risk | 80 (71.43) | 17 (51.52) | 63 (79.75) | |
bleeding risk of gastric varices | 0.005 | |||
low risk | 39 (34.82) | 18 (54.55) | 21 (26.58) | |
high risk | 73 (65.18) | 15 (45.45) | 58 (73.42) | |
