Fig. 2
From: Computable phenotypes to identify respiratory viral infections in the All of Us research program
Phenotype performance across different episode definitions. Specificity (a), sensitivity (b), and positive predictive value (PPV; c) were calculated using nucleic acid amplification and virus culture laboratory results as the reference standard. For each virus, colored lines show performance across episodes containing increasing numbers of ICD codes. For influenza virus (orange line) and SARS-CoV-2 (dark blue line), additional dashed lines show performance when episodes were restricted to episodes containing both ICD codes and antiviral prescriptions (Rx). *Y-axis for specificity (a) is broken to depict differences near 1.0. **Human coronavirus (hCoV) episodes excluded ICD codes after February 1, 2020, due to loss of specificity during the COVID-19 pandemic (Figure S1a). PIV: parainfluenza; hMPV: human metapneumovirus; RV: rhinovirus; ADV: adenovirus; RSV: respiratory syncytial virus; hCoV: human coronavirus; Flu: influenza virus.
