Table 8 Proposed drugs for repurposing in this study.

From: Drug repurposing targeting COVID-19 3CL protease using molecular docking and machine learning regression approaches

Sr. No.

Zinc ID

Generic name

Orignal purpose/treatment

New indication

1

ZINC003873365

Stanozolol

Hereditary angioedema (HAE), anemia, and certain forms of breast cancer.

COVID-19 3 CL

2

ZINC085432544

Vinblastine

Hodgkin’s and non-Hodgkin’s lymphoma, breast cancer, neuroblastoma, testicular cancer, histiocytosis, mycosis fungoides, and Kaposi’s sarcoma.

COVID-19 3 CL

3

ZINC203757351

Paritaprevir

Antiviral agent for Hepatitis C Virus (HCV) infections.

COVID-19 3 CL

4

ZINC085536956

Vinorelbine tartrate

Advanced or metastatic non-small cell lung cancer.

COVID-19 3 CL

5

ZINC008214470

Vindesine

Acute leukemia, malignant lymphoma, Hodgkin’s disease, acute erythremia, and acute panmyelosis.

COVID-19 3 CL

6

ZINC261494640

41-O-demethyl rapamycin

Tumor-based cancers prevent organ rejection in kidney transplant patients and coat stents implanted in heart disease patients.

COVID-19 3 CL

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