Fig. 8 | Scientific Reports

Fig. 8

From: Optimization and evaluation of an experimental subarachnoid hemorrhage model in mice

Fig. 8

Oligodendrocyte Injury and Proliferation, and Neuronal Damage in the Cortex and Striatum After SAH in mice. (a) Immunofluorescence images of Olig2 and NG2 in the corpus callosum (bregma − 0.5 mm) of sham and SAH mice. Scale bar = 100 μm. (b-c) Quantitative analysis of Olig2 and NG2 fluorescence in the corpus callosum of sham and SAH mice. n = 3. (d-g) Immunofluorescence images of NeuN staining in the cortex and striatum of sham and SAH mice. Scale bar = 100 μm. Quantitative analysis of NeuN fluorescence in the cortical and striatal regions of sham and SAH mice. n = 3. Note: * P < 0.05, ** P < 0.01, vs. sham group. SAH, Subarachnoid Hemorrhage; Olig2, Oligodendrocyte Transcription Factor 2; NG2: Neural/Glial Antigen 2 (marker for oligodendrocyte precursor cells); DAPI: 4′,6-diamidino-2-phenylindole (a nuclear stain); NeuN: Neuronal Nuclei (a marker for neurons).

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