Fig. 13

Regulatory changes in the glycolysis/gluconeogenesis pathway. Boxes indicate proteins, and circles indicate metabolites. The colors correspond with the pear proteins detected using TMT. Boxes are red for upregulation, green for downregulation, and black for no significant difference; the top half of the box indicates the DEPs at 10 WAF compared with those at 5 WAF and the bottom half of the box indicates the DEPs at 15 WAF compared with those at 10 WAF.