Fig. 1

Selection of optimal dose of berberine. (A) The chemical structural formula of berberine. The cell viability (B) and LDH levels (C) in the NIT-1 cells were detected by CCK-8 assay and kits after 0.2, 0.4 and 0.6 µM of berberine treatment. N = 3. *P < 0.05, **P < 0.01.