Table 1 Association of clinicopathological characteristics and CMS-resembling subtypes.

From: An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks

Clinicopathological

CMS1-like

CMS2-like

CMS3-like

CMS4-like

p value*

Variable

76 (15.8%)

168 (34.9%)

185 (38.5%)

52 (10.8%)

 

Age

     

  < 69

38 (50.0%)

93 (55.4%)

74 (40.0%)

28 (53.8%)

0.027

  ≥ 69

38 (50.0%)

75 (44.6%)

111 (60.0%)

24 (46.2%)

 

Sex

     

 Female

41 (53.9%)

78 (46.4%)

83 (44.9%)

24 (46.2%)

0.61

 Male

35 (46.1%)

90 (53.6%)

102 (55.1%)

28 (53.8%)

 

Stage (TNM I–IV)

     

 I

9 (11.8%)

37 (22.2%)

37 (20.0%)

7 (13.5%)

0.47

 II

25 (32.9%)

53 (31.7%)

52 (28.1%)

13 (25.0%)

 

 III

27 (35.5%)

56 (33.5%)

63 (34.1%)

23 (44.2%)

 

 IV

15 (19.7%)

21 (12.6%)

33 (17.8%)

9 (17.3%)

 

pT

     

 1

0 (0)

10 (6.0%)

8 (4.4%)

2 (3.8%)

0.249

 2

11 (15.1%)

35 (21.1%)

43 (23.6%)

8 (15.4%)

 

 3

52 (71.2%)

110 (66.3%)

112 (61.5%)

35 (67.3%)

 

 4

10 (13.7%)

11 (6.6%)

19 (10.4%)

7 (13.5%)

 

pN

     

 0

37 (50.0%)

93 (56.4%)

95 (52.5%)

22 (42.3%)

0.064

 1

23 (31.1%)

47 (28.3%)

53 (29.3%)

11 (21.2%)

 

 2

14 (18.9%)

26 (15.7%)

33 (18.2%)

19 (36.5%)

 

pM

     

 0

61 (80.3%)

146 (87.4%)

152 (83.5%)

43 (82.7%)

0.50

 1

15 (19.7%)

21 (12.6%)

30 (16.5%)

9 (17.3%)

 

Grade

     

 Low

57 (79.2%)

147 (90.7%)

158 (89.8%)

43 (84.3%)

0.056

 High

15 (20.8%)

15 (9.3%)

18 (10.2%)

8 (15.7%)

 

Tumor location

     

 Right colon

46 (60.5%)

29 (17.3%)

54 (29.2%)

12 (23.1%)

 < 0.001

 Left colon

10 (13.2%)

53 (31.5%)

45 (24.3%)

7 (13.5%)

 

 Rectum

20 (26.3%)

86 (51.2%)

86 (46.5%)

33 (63.5%)

 

Histology

     

 Non-mucinous

59 (84.3%)

144 (98.6%)

148 (92.5%)

44 (89.8%)

0.001

 Mucinous

11 (15.7%)

2 (1.4%)

12 (7.5%)

5 (10.2%)

 
  1. *Using the Fisher’s exact test.
  2. CMS-like, consensus molecular subtype resembling classification.