Table 4 Multiple adjusted ORs of implantation failure across different paternal age groups by maternal age and their differences for additive effect.

From: Effects of paternal age and interaction with smoking, alcohol consumption and maternal age on implantation failure in women undergoing ART

Paternal age

(year)

Maternal age ≥ 30 years

Maternal age 20-<30 years

Differences

in ORs

Participants,

n = 1021

OR†

95% CI

p

Participants,

n = 889

OR†

95% CI

p

All

IF (n, %)

   

All

IF (n, %)

   

ROR

P*

22-<35

593

222 (37.4)

1.00

  

851

282 (33.1)

1.00

    

35–57&1

428

221 (51.6)

1.65

1.25–2.19

< 0.001

38

10 (26.3)

0.72

0.33–1.59

0.418

2.29

0.027

  1. † Model 4 adjustment.
  2. &1 under maternal age ≥ 30 years, only one participate in the group of 40-<45 and one participant in the group of 45–57 (no event); thus these two groups were combined with the paternal age group of 35-<40 for analysis.
  3. * one-side p value.
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