Table 4 Multiple comparisons between patients with MCI, mild AD, moderate AD, and severe AD.

From: Lower water-soluble vitamins and higher homocysteine are associated with neurodegenerative diseases

Variable

MCI versus (p value)

Mild AD

Moderate AD

Severe AD

MMSE

0.003

< 0.001

< 0.001

MOCA

0.306

< 0.001

< 0.001

CDR

0.426

0.730

< 0.001

BNT

0.727

< 0.001

< 0.001

Duration

0.642

0.492

0.037

VB1

0.469

0.003

0.014

VB2

0.946

0.780

0.996

VB3

0.904

0.343

0.790

VB5

0.266

0.054

0.002

VB6

0.001

< 0.001

< 0.001

5mTHF

0.056

0.002

< 0.001

VC

0.002

0.136

0.018

VB12

0.857

1.000

0.273

Total folate

0.352

0.350

0.002

Hcy

0.392

0.355

0.018

  1. VB1 vitamin B1, VB2 vitamin B2, VB3 vitamin B3, VB5 vitamin B5, VB6 vitamin B6, 5mTHF 5-methyltetrahydrofolate, VB12 vitamin B12, VC vitamin C, Hcy homocysteine.
  2. Significant values are in bold.
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