Table 3 Comparison of clinicopathological characteristics among high-grade EPGA, low-grade EPGA, and ETGA.
From: Clinicopathological features and mucin expression of early papillary gastric adenocarcinoma
Characteristics | High-grade EPGA (n = 62) | Low-grade EPGA (n = 54) | ETGA (n = 116) |
|---|---|---|---|
Age (years) | 67.5 (61.0–71.0) | 66.5 (59.0–71.0) | 66.0 (59.0–71.0) |
Sex | |||
Male | 50 (80.6%) | 39 (72.2%) | 87 (75.0%) |
Female | 12 (19.4%) | 15 (27.8%) | 29 (25.0%) |
Location | |||
The cardia | 11 (17.7%) | 9 (16.7%) | 30 (25.9%) |
The fundus | 2 (3.2%) | 2 (3.7%) | 0 (0%) |
The corpus | 14 (22.6%) | 10 (18.5%) | 34 (29.3%) |
The pylorus | 35 (56.5%) | 33 (61.1%) | 52 (44.8%) |
Gross appearance | |||
Elevated | 30 (48.4%) | 33 (61.1%)# | 38 (32.8%) |
Non-elevated | 32 (51.6%) | 21 (38.9%) | 78 (67.2%) |
Ulcer formation | |||
Present | 10 (16.1%)### | 2 (3.7%) | 2 (1.7%) |
Absent | 52 (83.9%) | 52 (96.3%) | 114 (98.3%) |
Size (cm) | 2.25 (1.60–3.50)# | 2.05 (1.60–2.90)# | 1.30 (0.90–2.10) |
Differentiation | |||
Moderately | 42 (67.7%)### | 24 (44.4%) | 47 (40.5%) |
Well | 20 (32.3%) | 30 (55.6%) | 69 (59.5%) |
Invasion depth | |||
Mucosa | 45 (72.6%) | 49 (90.7%) | 103 (88.8%) |
Submucosa | 17 (27.4%)### | 5 (9.3%) | 13 (11.2%) |
Infiltrative pattern | |||
INFa | 45 (72.6%) | 51 (94.4%) | 96 (82.8%) |
INFb | 11 (17.7%) | 3 (5.6%) | 19 (16.4%) |
INFc | 6 (9.7%) | 0 (0%) | 1 (0.9%) |
LVI | |||
Present | 8 (12.9%)# | 3 (5.6%) | 3 (2.6%) |
Absent | 54 (87.1%) | 51 (94.4%) | 113 (97.4%) |
LNM | |||
Present | 2 (3.2%) | 0 (0%) | 0 (0%) |
Absent | 60 (96.8%) | 54 (100%) | 116 (100%) |
MUC2 | |||
High expression | 9 (14.5%) | 11 (20.4%) | 12 (10.3%) |
Low expression | 53 (85.5%) | 43 (79.6%) | 104 (89.7%) |
MUC5AC | |||
High expression | 38 (61.3%)# | 42 (77.8%)# | 28 (24.1%) |
Low expression | 24 (38.7%) | 12 (22.2%) | 88 (75.9%) |
MUC6 | |||
High expression | 25 (40.3%) | 30 (55.6%)# | 42 (36.2%) |
Low expression | 37 (59.7%) | 24 (44.4%) | 74 (63.8%) |
MSI status | |||
MSI-H | 12 (19.4%)# | 5 (9.3%) | 4 (3.4%) |
MSI-L/MSS | 50 (80.6%) | 49 (90.7%) | 112 (96.6%) |
P53 | |||
Wild type | 28 (45.2%) | 41 (75.9%)# | 57 (49.1%) |
Mutation type | 34 (54.8%)## | 13 (24.1%) | 59 (50.9%) |
Ki-67 | 70% (60–70%)### | 60% (40–70%) | 60% (40–70%) |
