Table 2 The results are presented as calculated IC50 values (concentration inhibiting 50% of cell growth) for both Palbociclib alone and Palbociclib combined with cisplatin. Additionally, combination indices are included to reveal the interaction between the drugs in HepG2 and Huh-7 cells. These indices likely indicate a synergistic effect, meaning the combined treatment is more effective than the sum of the individual drugs, in HepG2 cells. On the other hand, the data suggests an additive effect in Huh-7 cells, where the combination acts like the effects of each drug added together. 

From: Cisplatin palbociclib combination differentially modulates PTEN AKT signaling via Hsp90 in hepatocellular carcinoma cells