Fig. 1 | Scientific Reports

Fig. 1

From: Glymphatic dysfunction as a biomarker for post-stroke cognitive impairment

Fig. 1

The assessment process for the glymphatic function by calculating the DTI-ALPS index in non-stroke cohorts (A) and stroke cohort (B), and CP and PVS volume (C). The goal for the placement of the ROIs (yellow and orange rectangles) is to place them on their bilateral projection fibers (blue area) and association fibers (green area), respectively (D) in calculating DTI-ALPS index. The relationship between the direction of the perivascular space (orange cylinder) and the direction of the fibers. ALPS, diffusion tensor image analysis along the perivascular space; FA, fractional anisotropy; FLAIR, fluid-attenuated inversion recovery; ROI, region of interest; MNI, Mapping-Montreal Neurological Institute; CP, choroid plexus; PVS, perivascular space; WM, white matter; BG, basal ganglia.

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