Table 2 Description of the DTI-ALPS index levels in three cohorts.

From: Glymphatic dysfunction as a biomarker for post-stroke cognitive impairment

 

Non-stroke cohorts (n = 95)

Stroke cohort (n = 51)

Time 1 (n = 51)

Time 2 (n = 41)

Mean value

Healthy controls (n = 48)

n-VCI (n = 47)

Non-infarct side

FDR P value#

Infarct side

FDR P value&

Non-infarct side*

FDR P value*

Infarct side

FDR P value*

DTI-ALPS index

1.39 ± 0.24

1.45 ± 0.22

1.34 ± 0.25

1.32 ± 0.27

0.072

0.98 ± 0.30

 < 0.001

1.33 ± 0.25

0.832

1.09 ± 0.22

0.046

CP volume ratio

0.15 ± 0.04

0.13 ± 0.03

0.16 ± 0.03

0.13 ± 0.03

0.142

0.14 ± 0.04

0.449

0.14 ± 0.03

0.296

0.14 ± 0.04

0.475

BG-PVS volume ratio

0.02 ± 0.01

0.02 ± 0.01

0.02 ± 0.01

0.01 ± 0.01

0.004

0.02 ± 0.02

0.789

0.02 ± 0.01

0.360

0.02 ± 0.01

0.502

WM-PVS volume ratio

0.10 ± 0.03

0.10 ± 0.02

0.10 ± 0.03

0.09 ± 0.03

0.072

0.09 ± 0.03

0.283

0.09 ± 0.04

0.593

0.09 ± 0.03

0.604

  1. &Time 1 infarct side vs. non-stroke cohorts.
  2. #Time 1 non-infarct side vs. non-stroke cohorts.
  3. *Time 2 vs. Time 1.
  4. Mean value the mean value of bilateral level of each imaging marker, DTI-ALPS diffusion tensor image analysis along the perivascular space, n-VCI nonvascular cognitive impairment, CP choroid plexus, PVS perivascular space, BG basal ganglia, WM white matter, FDR false discovery rate.
Back to article page