Table 3 Threshold effect analysis for the relationship between the ΔDTI-ALPS index of infarct side and OTD.

From: Glymphatic dysfunction as a biomarker for post-stroke cognitive impairment

Models

ΔDTI-ALPS index of infarct side

P value

Adjusted β (95% CI)

P value

Crude β (95% CI)

Model I

 One line slope

− 0.001 (− 0.006, 0.004)

0.800

− 0.002 (− 0.005, 0.001)

0.219

Model II

 Turning point

42

 

42

 

 < 42 slope 1

0.029 (0.011, 0.047)

0.0032

0.010 (− 0.001, 0.021)

0.095

 > 42 slope 2

− 0.009 (− 0.016, − 0.002)

0.0106

− 0.004 (− 0.008, − 0.001)

0.024

 LRT test

 

0.001

 

0.016

  1. Model I. Linear analysis; Model II, nonlinear analysis. LRT test, logarithmic likelihood ratio test. A P value < 0.05 indicated that Model II was significantly different from Model I, which indicated a nonlinear relationship. Crude: no adjustment; Adjusted: adjusted for age and number of lacunes. ΔDTI-ALPS index, changes in the DTI-ALPS index between Time 1 and Time 2 MRI scan; ODP, the days from stroke onset to the Time 1 MRI scan.
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